Programmable tech used at King’s to control seizures

25 June 2018 - First operation of its type in Europe for Surrey school boy

Dr McCormick with patient, Simukai Shambira

King’s College Hospital in south London has become the first centre in Europe to implant a new generation brain stimulation device that uses scheduled programming to suppress the frequency and severity of epileptic seizures.

King’s has a long history of treating patients with medication-resistant epilepsy who are not candidates for direct surgery to the brain. The treatment used is Vagus Nerve Stimulation (VNS). VNS involves implanting a small device in the chest and connecting it to the vagus nerve in the neck where it delivers electrical impulses to the brain to relieve seizures.

The current delivered is gradually increased by a doctor in during outpatient appointments and the programming cycle is changed to optimise the management of seizures. The patient or carer is able to ‘swipe’ the device with a magnet when a seizure occurs to deliver a booster dose of stimulation, and since January 2015 the device has also been able to continuously monitor heart rate and deliver additional stimulation when a rise in heart rate consistent with a seizure occurs. VNS has been shown to be effective in decreasing the frequency and severity of seizures, allowing a decrease in medication, and in improving patients’ quality of life.

The new device allows the doctor to programme it in a more flexible manner. Multiple steps can be pre-programmed to occur at specified times in the future so that the patient is not required to attend as many outpatient appointments. The device can also be programmed to deliver different stimulation patterns at different times of the day or night, according to the patient’s condition. In outpatient appointments the doctor is able to download the record of seizure detections from the device and see the pattern by date and even hour of the day.

Dr David McCormick, Consultant Paediatrician in Epilepsy and Neurorehabilitation, and a leading expert on VNS therapy said, “Implantable technology will play a key part in the future of personalised medicine. This implanted device is the next generation treatment for patients with drug-resistant epilepsy. We are hopeful that it will offer further improvements in seizure control and quality of life for patients.”

Nine-year-old Surrey schoolboy, Simukai Shambira, was the first patient in Europe to have the new device implanted, Simukai has Lissencephaly, a rare genetic condition characterised by the absence of the normal folds in the brain, which results in several seizures per day.

His father, Valentine Shambira, who lives in Wallington, Surrey with his wife Felistas, Simukai and two younger sons, and said, “Simukai was on three different types of medication to control his seizures but he became resistant to the medication so we had to find a different treatment, which was when the team at King’s College Hospital told us about this new technology.

“We hope this device will reduce the number of seizures Simukai experiences each day. The fits slow him down and make him very drowsy so he misses out at school. We don’t live near the hospital so not having to attend appointments as frequently will help us to have more of a normal family life.”

Dr McCormick added, “This device is win-win: it means fewer hospital appointments for patients and this also means that over time it will save the NHS money. The device is also smaller than the ones we have used previously so it is less obvious underneath the skin.”


For further information please contact:
Karen Welsh
Acting Head of Communications
karen.welsh2@nhs.net
Extension: +44 (0)20 3299 3850

Notes to editors

1. King’s College Hospital NHS Foundation Trust is one of the UK’s largest and busiest teaching hospitals, training over 900 dentists, 750 doctors and 300 nurses every year. The Trust is recognized internationally for its work in liver disease and transplantation, neurosciences, cardiac, haemato-oncology, stroke and major trauma. On 1 October 2013, King’s took over the running of the Princess Royal University Hospital in Bromley and Orpington Hospital, as well as some services at Beckenham Beacon and Queen Mary’s Hospital, Sidcup. The new enlarged organisation has over 10,500 staff and provides over 1 million patient contacts a year. 9,000 babies are delivered by our hospitals each year, and over 750 patients come to our Emergency Departments every day. For more information, please visit the website. You can also support the work of King’s College Hospital at www.togetherwecan.org.uk

2. King’s Health Partners Academic Health Sciences Centre (AHSC) is a pioneering collaboration between King’s College London, and Guy’s and St Thomas’, King’s College Hospital and South London and Maudsley NHS Foundation Trusts.

King’s Health Partners is one of only six Department of Health-designated AHSCs in England and brings together an unrivalled range and depth of clinical and research expertise, spanning both physical and mental health. Our combined strengths will drive improvements in care for patients, allowing them to benefit from breakthroughs in medical science and receive leading edge treatment at the earliest possible opportunity.

Our partnership brings together...

  • three of the UK’s leading NHS Foundation Trusts;
  • one of the top 30 universities in the world;
  • services provided over 225 locations, including seven hospitals and community and mental health centres;
  • 2.2 million patient contacts each year;
  • 31,000 staff;
  • 25,000 students;
  • a combined annual turnover of £2.8bn.

... to advance health and wellbeing by integrating world-class research, care and teaching.

3. At King’s College Hospital we fundraise for the best in treatment, research and health education, leading-edge equipment and improving well-being in our communities. By uniting doctors, nurses, researchers and academics with our supporters and volunteers we can provide the best patient care that goes above and beyond. Find out more and support us at togetherwecan.org.uk